
江伯倫 合聘教授
- 研究專長黏膜免疫學、細胞免疫調控和應用
- 學術經歷美國加州大學戴維斯分校博士 (台大生命科學院院長)
- 聯絡電話+886-2-2312-3456 #267302
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電子信箱
gicmbor@ntu.edu.tw
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個人網頁
https://scholars.lib.ntu.edu.tw/entities/person/4fd28594-f41b-4c6f-b1a4-c109032b7c1b
學歷
- 1987-1991 博士 美國加州大學戴維斯分校免疫學
- 1976-1983 學士 國立臺灣大學醫學系
經歷
- 主治醫生 國立臺灣大學醫學院附設醫院小兒部
- 1999- 教授 國立臺灣大學臨床醫學研究所
- 2017-2020 理事長 臺灣兒科醫學會
- 2014-2020 教學研究副院長 國立臺灣大學附設醫院
- 2013-2016 理事長 臺灣過敏氣喘和臨床免疫學會
- 2013 共同主席 亞太過敏氣喘和臨床免疫學會
- 2012-2015 所長 國立臺灣大學免疫學研究所
- 2008 主席 亞太免疫學會2008年大會
- 2004-2006 理事 亞太免疫學會
- 2003-2009 主任 國立臺灣大學附設醫院小兒科
- 2003-2006 理事長 中華民國免疫學會
- 2002-2005 常務監事 中華民國兒童過敏免疫學會
- 2002-2004 組長 國立臺灣大學附設醫院醫學研究部訓練規劃組
- 2002-2004 主任 國立臺灣大學醫學院實驗動物中心
- 1999-2002 組長 國立臺灣大學附設醫院醫學研究部實驗研究組
- 2001 理事 亞太兒童過敏及臨床免疫學會
- 2001 理事 臺灣保健食品學會
- 2000 副秘書長兼學術委員會副主任委員 第十屆亞洲小兒科醫學會
- 1999-2002 理事 中華民國小兒科醫學會
- 1999-2002 常務理事 亞太兒童過敏及臨床免疫學會
- 1999 執行理事 亞太過敏及臨床免疫學會
- 1999 執行長 財團法人兒童過敏及氣喘病學術文教基金會
- 1997-2003 常務理事 中華民國免疫學會
- 1997-1999 理事長 臺灣兒童過敏免疫學會
- 1995-1998 執行理事兼助理秘書長 亞太過敏及臨床免疫學會
- 1995 副祕書長 第二屆亞太過敏免疫學會
- 1995-1998 藥政委員 衛生署
- 1991-1999 副教授 國立臺灣大學臨床醫學研究所
獎項和榮譽
- 2019 李國鼎管理獎章
- 2018 第十六屆有庠科技講座
- 2016 第六十屆教育部學術獎
- 2016 第二十三屆東元獎
- 2014 臺大特聘教授
- 2012 臺大醫院傑出研究團隊
- 2012 第七屆李天德卓越醫藥科技獎
- 2009 臺灣醫學會學術演講獎
- 2008-2010 國科會傑出學者研究計畫
- 2008 第六屆有庠傑出教授獎
- 2005 臺灣保健食品學會傑出學術研究獎
- 2005 臺大醫院傑出研究獎
- 2004, 2010, 2013 國科會及科技部傑出研究獎
- 2004 景福基金會研究貢獻獎(SARS研究團隊成員)
- 2004 名儕吳天賜先生文教基金會傑出研究獎
- 2004 北美校友會最佳臨床教師獎
- 2003,2007,2009,2013, 2017, 2018 臺大教學優良教師
- 2002 跨世紀基金會研究獎助
- 2002 第十二屆王民寧醫藥研究傑出貢獻獎
- 2001 莊淑綺女士傑出醫學研究獎
- 1998 藤澤醫學研究獎助
- 1998 第三十六屆中華民國十大傑出青年
- 1997 臺大醫院醫學研究特殊優異獎
- 1997 Pharmacia-Upjohn Research Award
- 1996 魏火曜兒科優秀論文獎
- 1995,1999 Abbott New Categorical Research Award
- 1995,1997 Nestle Research Award
- 1990 Travel Award for graduate student, UC Davis
- 1989-1991 Non-resident tuition and fee fellowship, UC Davis
一.過敏疾病的新治療研發:我們研究團隊在過去幾年間一直努力於將細胞激素基因和RNAi應用到過敏疾病的治療上,得到相當優異的研究成果。目前在這方面的review
articles有許多都是來自我們研究室,而且國際上較有名的期刊收到有關過敏疾病的基因療法的論文時也都經常找我們擔任審查委員。這些研究成果都顯示我們研究團隊在這方面的研究受到相當多的重視,甚至在國際上已經居於領導地位。
此外,我們也建立了方法來篩選可以應用到氣喘治療的藥物。主要是利用樹突細胞來作為篩選藥物的平台。我們與台大漁業科學研究所的周宏農教授合作之下,由紅毛苔的分離物中篩選到一個藻藍蛋白(R-PC),具有調節免疫功能的能力,發現可以有效地降低氣喘動物模式的IgE濃度,同時可以改善呼吸道的發炎和阻力。目前此一R-PC化合物已經申請美國和台灣的專利,而且研究結果也已經發表在2012年呼吸系統領域排名第一的American
Journal of Respiratory and Critical Care Medicine。目前也在進一步研究其他可能應用到過敏疾病治療的藥物。
二.此外,我們在過去一段期間也一直努力於研究有關口服耐受性在免疫疾病的機轉。我們建立基因轉殖植物表現塵mite過敏元蛋白也已經應用到氣喘的動物模式,明顯的可以觀察到可以降低過敏原的IgE抗體和改善呼吸道的發炎和阻力,此一研究成果已經發表在今年的Cellular
and Molecular
Immunology。目前我們也正在利用由黏膜分離出來的B細胞來誘發出具有調節能力的T細胞,研究其未來的應用和在黏膜誘發耐受性的機轉。利用此一黏膜B細胞誘發出的調節性T細胞已經在試管內可以有效地抑制T細胞的增殖反應,同時可以在氣喘的小鼠模式有效地改善呼吸道的發炎。此一研究成果也已經發表在American
Journal of Respiratory Molecular and Cellular Biology、Cellular and Molecular Immunology及Clinical and Experimental
Immunology。最近並利用這些調節性T細胞的特性進行有關過敏原應用在免疫療法的研究,也已經為在此一領域排名第一的Journal of Allergy and Clinical Immunology所接受發表。
三.我們最近在肺部幹細胞找到一群SSEA-1+的肺部幹/前驅細胞,發現在肺部發炎疾病中扮演一個重要的角色,目前已經將成果寫成論文和被Allergy期刊所接受,而且被選為2015年四月份的封面。
四.此外,我們研究團隊也積極從事於臨床研究,其中包括異位性皮膚炎的睡眠研究。異位性皮膚炎的患童由於皮膚的病變極度具有癢感,所以常常會抓得非常厲害,甚至影響到睡眠品質,而在睡覺時無意識地抓傷也會導致病兆的惡性循環。所以我們就針對這些異位性皮膚炎患童的睡眠品質和褪黑激素(melatonin)的角色進行研究,同時也給予這些患童額外的褪黑激素看是否能夠改善這些患童的睡眠品質和臨床症狀。這些研究成果有一篇已經為Pediatrics所接受,而另外一篇則是2015年十一月在JAMA
Pediatrics發表。這兩個雜誌都是在小兒科領域中最好的論文期刊,顯示我們的研究成果已經受到國際上的重視。
我們的研究成果已經在國際上佔有重要的地位;因此個人也受邀擔任國際知名期刊,Journal of Autoimmunity和Clinical and Experimental Allergy的編輯群。此外,單是這兩年我們的研究團隊就受到如Journal of Autoimmunity、Autoimmunity Review和Clinical Review on Allergy and Immunology相當好的期刊邀請寫了數篇綜論性文章,由這些成果顯示我們團隊的研究成果已經在相關研究領域中已經受到相當多的肯定。
- 2016 Chang, Y.-S., Lin, M.-H., Lee, J.-H., Lee, P.-I., Dai, Y.-S., Lin, Y.-T., Wang, L.-C., Yu, H.-H., Yang, Y.-H., Chen, C.-A., Wan, K.-S. and Chiang, B.-L. Melatonin supplement for children with atopic dermatitis and sleep disturbance- A randomized, double –blind, placebo-controlled crossover study. JAMA Pediatrics 170: 35-42.*
- 2016 Huang, M.-T., Lin, B.-R., Lu, C.-W. and Chiang, B.-L. Lymph node trafficking of regulatory T cells is prerequisite for immune suppression. J Leukocyte Biol 99: 561-568.*
- 2016 Su, M.-W., Lin, W.-C., Tsai, C.-H., Chiang, B.-L., Yang, Y.-H., Lin, Y.-T., Wang, L.-C., Lee, J.-H., Chou, C.-C., Wu, Y.-F., Wu, W.-C., Chen, Y.-C., Yeh, Y.-L. and Lee, YL. Childhood asthma clusters reveal different clinical characteristic and gene signature. J Allergy Clin Immunol (Revised)
- 2016 Shu, C.-C., Wang, J.-Y., Wu, M.-F., Wu, C.-T., Lai, H.-C., Lee, L.-N., Chiang, B.-L., Yu, C.-J. and Yang, P.-C. Attenuated lymphocyte immune response in Mycobacterium avium complex-lung disease by increasing the expression of programmed death-1 receptor. Scientific Report 7:42004.
- 2016 Chen Y.-L. and Chiang, B.-L. Targeting TSLP with shRNA alleviated airway inflammation and decreased epithelial CCL17 in a murine model of asthma. Mol Therapy-Nucleic Acids 5: e316*
- 2016 Chen, S.-Y., Hsu, W.-T., Chen, Y.-L., Chien, C.-H. and Chiang, B.-L. LAG3+ Foxp3- regulatory T cells induced by B cells alleviated joint inflammation in collagen-induced arthritis. J Autoimmun 68:75-85.*
- 2016 Chang, Y.-S. and Chiang, B.-L. Melatonin-induced nocturnal vasodilation contributes to skin regeration-Reply . JAMA Pediatrics 170:622.*
- 2016 Chang, Y,-S. and Chiang, B.-L. Mechanism of sleep disturbance in children with atopic dermatitis and the role of the circadian rhythm and melatonin. Int J Mol Med 29:17.*
- 2016 Lin, S.-C., Huang, J.-J., Wang, J.-Y., Chuang, H.-C., Chiang, B.-L. and Ye, Y.-L. Upregulated thymic stromal lymphopoietin receptor expression in children with asthma. Euro J Clin Invest 46:511-519.
- 2016 Huang, M.-T., Chen, Y.-L. and Chiang, B.-L. Location, Location, Location- Positioning regulatory T cells to the right place at right time. Inflammation and Cell Signaling (In press)*
- 2016 Lin, H.-C., Lin, H.-P., Yu, H.-H., Wang, L.-C., Lee, J.-H., Lin, Y.-T., Yang, Y.-H., Li, P.-Y., Wei-Zen Sun, W.-Z. and Chiang, B.-L. Tai-Chi-Chuan exercise decreases airway inflammation, improves pulmonary function and quality of life in asthmatic children. eCAM (In press)*
- 2016 Chen, Y.-C, Liou, T.-H., Chen, P.-C., Chiang, B.-L. Yang, Y.-H., Fan, H.-Y. and Lee, Y.-L. Growth trajectory and asthma/ rhinitis in children: A longitudinal study in Taiwan. European Respiratory Journal. (In press)
- 2016 Shao, T.-Y., Hsu, L.-H., Chien, C.-H. and Chiang, B.-L. Novel Foxp3- IL-10- regulatory T cells induced by B cells alleviate intestinal inflammation in vivo. Scientific Report 6:32415*
- 2016 Tsai, W.-C., Wu, T.-C., Chiang, B.-L. and Wen H.-W. Cloning, expression and purification of recombinant major mango allergen Man i1 in Escherichia coli. Protein Expr Purif 130:35-43.
- 2017 Huang, M.-T., Liu, W.-L., Chen, Y.-L., Lien, C.-I., Hsu, L.-C. and Chiang, B.-L. Divergent roles of Jagged 1 and DLL4 in allergic airway disease. Scientific Reports 7: 43535.*
- 2017 Chien, C.-H., Yu, H.-C., Chen, S.-Y. and Chiang, B.-L. Naïve B cells induced c-Maf+ IL-10-producing regulatory T cells with suppressive activity through IL-10 and CTLA-4. Scientific Reports 7: 46348.*
- 2017 Shu, C.-C., Wu, M.-F., Wang, J.-Y., Lai, H.-C., Lee, L.-N., Chiang, B.-L., and Yu, C.-J. Decreased T helper 17 in tuberculosis is associated with increased percentage of programmed death ligand-1, T helper cell and regulatory T cells. Respir Res 18:128*
- 2017 Su, Y., Yang, Y.-H. and Chiang, B.-L. Long-trem responses to Etanercept in methotrexate refractory-juvenile idiopathic arthritis. Clin Rheumatol 36:1997-2004.
- 2017 Lin, S.-C., Chou, H.-C., Chiang, B.-L., Chen, C.-M. CTGF Up-regulation correlates with MMP-9 level in airway remodeling in a murine model of asthma. Arch Med Sci 13:670-676.
- 2017 Chen, H.-J., Hsu, C.-H. and Chiang, B.-L. Serum retinol levels and neonatal outcomes in preterm infants. J Formos Med Assoc (In press)*
- 2017 Lee, Y.-L., Chiang, C.-Y., Lee, C.-C., Fan, C.-K., Huang, H.-M., Chiang, B.-L. Osthole treatment ameliorates Th2-mediated allergic asthma and exerts immunomodulatory effects on dendritic cells maturation and function. Cell Mol Immunol (In press)
- 2017 Chien, C.-H. and Chiang, B.-L. Regulatory T cells induced by B cells: A novel subpopulation of regulatory T cells. J Biomed Sci 24: 86*
- 2017 Lin, S.-C., Lin, H.-W. and Chiang, B.-L. Association of croup with asthma in children: A cohort study. Medicine 96:e7667
- 2017 Wu, Y.-F., Su, M.-W., Chiang, B.-L., Yang, Y.-H., Lin, Y.-T., Wang, L.-C., Lee, J.-H., Chou, C.-C., Yeh, Y.-L. Tsai, C.-H and Lee, Y. A simple prediction for tool for inhaled corticoid response in asthmatic children. BMC Pulm Med 17:176
- 2018 Chua, H.-H., Chou, H.-C., Tung, Y.-L., Chiang, B.-L., Liao, C.-C. and Ni, Y.-H. Gut dysbiosis featured by abundant Ruminococcus gnavus heralds the manifestation of allergic diseases in infants. Gastroenterology 154:154-167.
- 2018 Chieh, C.-H. and Chiang, B.-L. Recent advance on regulatory T cells induced by B cells. Cell Mol Immunol 15:539-541.*
- 2018 Chang-Chien C.-Y., Chuang, G.-T., Tsai, I.-J., Chiang, B.-L. and Yang, Y.-H. Etiology of significant persistent proteinuria in children. J Formos Med Assoc 117: 711-719.
- 2018 Yu, H.-C., Chiang, B.-L. Toll-like receptor-2 ligation of mesenchymal stem cells alleviate airway inflammation. J Allergy Clin Immunol 142: 284-287.*
- 2018 Chang, Y.-S. and Chiang, B.-L. Sleep disorder and atopic dermatitis: A two-way street? J Allergy Clin Immunol 142:1033-1040.*
- 2018 Yeh, Y.-L., Su, M.-W., Chiang, B.-L., Yang, Y.-H., Tsai, C.-H. and Lee, LY. Genetic profile from transcriptomic cluster of childhood asthma determines specific severe phenotypes. Clin Exp Allergy 48:1164-1172.
- 2018 Lin, Y.-L., Chow, Y.-H., Huang, L.-M., Hsieh, S.-M., Cheng, P.-Y., Hu, K.-C. and Chiang, B.-L. A CpG-adjuvanted intranasal enterovirus 71vaccine elicits mucosal and systemic immune responses, and protects human SCARB2-transgenic mice against lethal challenge. Sci Reports 8: 10713.*
- 2018 Lin, Y.-L., Cheng, P.-Y., Chin, C.-L., Huang, L.-M., Lin, S.-Y. and Chiang, B.-L. Fibroblast-stimulating lipopeptide-1 as a potential mucosal adjuvant enhances mucosal and systemic immune responses to enterovirus 71 vaccine. Vaccine 36:4331-4338.*
- 2018 Shu, C.-C., Chiang, B.-L. and Yu, C.-J. Interleukin 23 / interleukin 17 axis activated by Mycobacterium avium complex (MAC) is attenuated in patients with MAC-lung disease. Tuberculosis 110:7-14.
- 2018 Hung, K.-H., Woo, Y.H., Lin, I.-Y., Liu, C.-H., Wang, L.-C., Chen, H.-Y., Yang, S.-Y., Chiang, B.-L. and Lin, K.-I. The Jmjd2a/Jmjd2c/NF-kB and Wdr5 epigenetic cascade regulates the activation and differentiation of B cells. Nucleic Acid Reaserch 46:5547-5560.
- 2018 Su, M.-W., Lin, W.-C., Tsai, C.-H., Chiang, B.-L., Yang, Y.-H., Lin, Y.-T., Wang, L.-C., Lee, J.-H., Chou, C.-C., Wu, Y.-F., Yeh, Y.-L., Lee, Y.-L. Childhood asthma clusters reveal neutrophil-predominant phenotype with distinct gene expression. Allergy 73:2024-2032.
- 2018 Wang, L.-J., Yu, Y.-H., Fu, M.-L., Yeh, W.-T., Hsu, J.-L., Yang, Y.-H., Chen, W.-J., Chiang, B.-L and Pan W.-H. Attention deficit-hyperreactivity disorder is associated with allergic symptoms and low levels of hemoglobin and serotonin. Scientific Report 8:10229.
- 2019 Lin, H.-P., Chiang, B.-L., Yu, H.-H.., Lee, J.-H., Lin, Y.-T., Yang, Y.-H., and Wang, L.-C. The influence of breast-feeding in breast-fed infants with atopic dermatitis. J Microbiol Immunol Infect 52: 132-140
- 2019 Yu, H.-H., Hu, T.-C., Lee, N.-C., Chien, Y.-H., Yang, Y.-H., Hwu, W.-L. and Chiang, B.-L. Mycobacterium Abscessus Infection in a boy with X-linked Anhidrotic Ectodermal Dysplasia, Immunodeficiency. J Microbiol Immunol Infect 52: 504-506.*
- 2019 Lee, J.-H. Y.-T. Shih, M.-L. Wei, C.-K, Sun and Chiang, B.-L. Classification of established atopic dermatitis in children with in vivo imaging methods. J Biophotonics 12:e201800148.*
- 2019 Tsai, W.-T., Chang, H.-C., Wang, C.-T., Chiang, B.-L., Lin, Y.-T. Long-term outcomes in lupus patients receiving different renal replacement therapy. J Microbiol Immunol Infect (In press)
- 2019 Wang, L.-J., Yu, Y.-H., Fu, M.-L., Yeh, W.-T., Hsu, J.-L., Yang, Y.-H., Yang, H.-T., Huang, S.-Y., Wei, I.-L., Chen, W.-J., Chiang, B.-L. and Pan, W.-H. Dietary profiles, nutritional biochemistry status, and attention/hyperreactivity disorder: Path analysis for a case-control study. J Clin Med (e-Pub)
- 2019 Lin, S.-C., Chou, H.-C., Chen, C.-M. and Chiang, B.-L. Anti-thymic stromal lymphopoietin antibody suppresses airway remodeling in asthma through reduction of MMP and CTGF. Pediatr Res 86: 181-187.
- 2019 Yeh, Y.-L., Wu, W.-C., Kannagi, R., Chiang, B.-L., Liu, F.-T. and Lee, Y.-L. Sialyl glycan expression on T cell subsets in asthma: a correlation with disease activity and blood parameters. Sci Rep. 9: 8947.
- 2019 Hu, Y.-C., Yang, Y.-H., Lin., Y.-T., Wang, L.-C., Yu, H.-H., Lee, J.-H. and Chiang, B.-L. Clinical manifestations and anti-TNF alpha therapy of juvenile Behcet’s disease. BMC Pediatr 19:232.
- 2019 Huang, M.-T. and Chiang, B.-L. Multi-faceted notch in allergic airway inflammation. Int J Med Sci. 20:E3508.*
- 2019 Liou, Y.-M., Wei, T.-Y., Ling, T.-Y., Lin, S.-C., Yang, Y.-H., Chiang, B.-L. and Chuang, Y.-H. Differential effects of mesenchymal stem cells on T cells isolated from childhood allergies and autoimmune diseases. Allergy 74: 2006-2010.
- 2019 Liao, P.-C., Lin, H.-H., Chiang, B.-L., Lee, J.-H., Yu, H.-H., Lin, Y.-T., Yang, Y.-H., Li, P.-Y., Wang, L.-C. and Sun, W.-Z. Tai Chi exercise improves lung function and asthma control through immune regulation and childhood asthma. eCAM 2019: 9146827.
- 2019 Shih, Y.-J., Yang, Y.-H., Lin, C.-Y., Chang, C.-L. and Chiang, B.-L. Enthesis-related arthritis is the most common category of juvenile idiopathic arthritis in Taiwan and presents persistent active disease. Pediatr Rheumatol 17:58.
- 2019 Lin, S.-C., Liou, Y.-M., Ling, T.-Y., Chuang, Y.-H. and Chiang, B.-L. Placenta-derived mesenchymal stem cells reduce interleukin-5 level experimentally in children with asthma. Int. J. Med. Sci 16:1430-1438.
- 2019 Kang, C.-M., Wu, E.-T., Wamg, C.-C., Lu, FL, Chiang, B.-L. and Yen, T.-A. Bilevel positive airway pressure ventilation efficiently improves respiratory distress in initial hours treating children with severe asthma exacerbation. JFMA 119:1415-1421.
- 2019 Wang, L.-C., Huang, Y.-M., Shen, P.-T., Huang, H.-Y., Chiang, B.-L. and Lin, B.-F. Lower Vitamin D level in the breast milk for atopic dermatitis infants. Pediatr Allergy Immunol 31: 258-264.
- 2020 Lin, S.-C., Chiang, B.-L., Lee, Y.-J., Chang, Y.-T. and Fang, S.-B. Pseudomonas aeruginosa sepsis presenting as ecthyma gangrenosum in identical twins with Bruton tyrosine kinase gene mutation: Report of two cases and review of literature. J Microbiol Immunol Infect 53:1030-1034.
- 2020 Hsu, W.-T., Huang, W.-J., Chiang, B.-L. Wu, C.-C., Tseng, P.-H. Butyrate-enhanced immunomodulation of adipose-derived stem cells in a spontaneous mouse model of metabolic syndrome. Cytotherapy (In press)
- 2020 Tsai, C.-H., Wu, A.-C., Chiang, B.-L., Yang, Y.-H., Hung, S.-P., Su, M.-W., Chang, J.-J. and Lee, Y.-L. CEACAM3 decreases symptomatic asthma and modulates respiratory syncytial virus latent infection in children. Thorax 75:725-734.
- 2020 Kang, J.-M. Chiang, B.-L. and Wang, L.-C. Maternal Nutritional Status and development of atopic dermatitis in their offsprings. Clin Rev Allergy Immunol (In press)
- 2020 Liao, C.-H., Lee, N.-C., Jou, S.-T., Chiang, B.-L. and Yu, H.-H. UNC13D mutation presenting as fulminant familial hemophagocytic lymphohistiocytosis. J Microbiol Immunol Infect (In press)
- 2020 Yang, Y.-W., Tsai, M.-K., Yang, C.-Y., Lee, C.-Y., Chiang, B.-L. and Lai, H.-S. Telbivudine for renal transplant recipients with chronic B infection: a randomized controlled trial with early termination. Clin Exp Nephrol 24:474-482.
- 2020 Yu, H.-H., Yang, Y.-H. and Chiang, B.-L. Chronic granulomatous disease: A Comprehensive Review. Clin Rev Allergy Immunol (In press)*
- 2020 Tang, N., Lu, C.-Y., Sue, S.-C., Chen, T.-H., Jan, J.-T., Huang, M.-S., Huang, C.-H., Chiang, B.-L., Huang, L.-M. and Wu, S.-C. Type IIb heat labile enterotoxin B subunit as a mucosal adjuvant enhances immunity against H5N1 avian fluenza virus. Vaccines 8: 710.
- 2020 Yang, C.-A. and Chiang, B.-L. Inflammasomes and childhood autoimmune diseases: A review of current knowledge. Clin Rev Allergy Immunol 25:1-15.*
- 2020 Liao, H.-T., Chiang, B.-L. and Tsai, C.-Y. Bruton’s tyrosine kinase in systemic lupus erythematosus. Joint Bone Spine (In press)
- 2020 Yang, C.-T., Chiang, B.-L. and Wang, L.-C. Aggressive corticosteroid treatment in childhood idiopathic pulmonary hemosiderosis with better outcome. JFMA 20: 30212-30216.
- 2020 Wang, L.-C. and Chiang, B.-L. Early-onset-early-resolving atopic dermatitis does not increase the risk of development of allergic diseases at 3 years old. JFMA (In press)*
- 2020 Liu, W.-D. Chang, S.-Y., Lan, T.-Y., Lin, Y.-C., Kao, J.-H., Liao, C.-H., Tsai, M.-J., Kuo, P.-H., Huang, Y.-S., Wang, J.-T., Sheng, W.-H., Hsieh, S.-C., Chiang, B.-L., Chen, Y.-C. and Chang, S.-C. Experience of the use of hydroxychroloquine on patients with COVID-19: A presepective on viral load kinetics. JFMA (In press)
- 2020 Huang, Y.-H., Hu, Y.-C., Liao, C.-H., Chiang, B.-L., Lu, C.-H., Li, K.-J., Yang, Y.-H. A single indicator joint in non-systemic juvenile idiopathic arthritis whose ultrasound scores are correlated with disease activity. Pediatr Rheumatol (In press)
- 2020 Luo, K.-L., Yang, Y.H., Lin, Y.-T., Hu, Y.-C., Yu, H.-H., Wang, L.-C., Chiang, B.-L. and Lee, J.-H. Differential parameters between activity flare and acute infection in pediatric patients with systemic lupus erythematosus. Scientific Report 10: 19313
- 2020 Liao, C.-H., Tsai, M., Yang, Y.H., Chiang, B.-L. and Wang, L.-C. Onset age is a risk factor for refractory pediatric IgA vasculitis: A retrospective cohort study. Pediatr Rheumatol 18:86.
- 2020 Lin, Y.-L., Shih, CH, Cheng, P.-Y., Chin, C.-L., Liou, A.-T., Lee, P.-Y. and Chiang, B.-L. A polysaccharide isolated from Ganoderma lucidum acts as a potent mucosal adjuvant that promotes protective immunity and protects mice against the Enterovirus lethal challenge. Front Immunol 11:561758.*
- 2020 Huang, T. T.-M., Chien, Y.-C., Wang, C.-H., Tolwani, A., Chang, S.-Y., Wang, J.-T. Hsieh, S.-C., Ku, S.-C., Yu, C.-J., Chiang, B.-L. and Chang, S.-C. Successful treatment of a critically ill COVID-19 patient using continuous renal replacement therapy with enhanced cytokine removal and Tocilizumab. Frontiers in Medicine (In press)
- 2021 Chang-Chien C. Chiang, B.-L. and Yang, Y.-H. Macrophage activation syndrome in pediatric rheumatic diseases other than systemic juvenile idiopathic arthritis. Clin Rev Allergy Immunol (Revised)
- 2021 Lin, Y.-T., Lin, C.-F., Lin, Y.-F., Chiang, B.-L. and Yeh T.-H. Clinical characteristics and cytokine profiles of central compartment type chronic rhinosinusitis. International Forum of Allergy & Rhinology (In press)
- 2021 Huang, J.-H. and Chiang, B.-L. Regulatory T cells induced by B cells suppress NLRP 3 inflammasome activation and alleviate monosodium urate-induced gouty inflammation. iScience 24: 102103*
- 2021 Lin, T.-S., Lee, J.-H., Wang, L.-C., Yang, Y.-H., Lau, Y.-L., Lee, W.-I., Chiang, B.-L. and Yu, H.-H. Clinical features and outcomes of patients with chronic granulomatous disease. J Clin Immunol (Revised)
- 2021 Chu, K.-H., Lin, S.-Y. and Chiang, B.-L. STAT6 is critical for regulatory T cells induced by mucosal B cells to alleviate airway inflammation. Frontiers Immunol 11: 615868*
- 2021 Liao, C.H., Chiang, B.-L. and Yang, Y.-H. Tapering of biological agents in juvenile ERA patients in daily clinical practice. Frontiers in Medicine (Revised)
- 2021 Sheu, T.-T. and Chiang, B.-L. Lymphopenia, lymphopenia-induced proliferation and autoimmunity. Int J Mol Sci (Revised)